"Tom Cruise is in the closet!"
The South Park episode ‘Trapped In The Closet’ was really mean to Tom by making rude jokes about Scientology and featuring a rumour-riffing spoof where Cruise refuses to emerge from a closet. A repeat of the episode was unexpectedly canned which, due to pressure from Cruise or not, was a big publicity own goal.
On the promotional trail for War Of The Worlds (2005) Tom let fly with some unusually candid statements about psychiatry and the treatment of mental illness. (“Psychiatry is a pseudo-science...” “There's no such thing as a chemical imbalance...” and, er, “You don’t even know what Ritalin is!”.) We admire folks who stand up for what they believe in - but still, those Martians, eh?