Stephen Colbert - Spider-Man

Appeared in: Amazing Spider-Man #573

Okay, so Colbert's more of a comedian than an actual politician, but he's here because a) He found fame in Comedy Central's political satire The Daily Show and b) He appears as a candidate for the US Presidency in the Marvel Universe. Which, obviously, is quite ace. Good work Stan Lee.

Who should play him in the film version: Well, himself. He does play The President of the United States in Monsters vs. Aliens, after all.