Chimera (Resident Evil)
Why you wouldn't want to meet it up a dark alley: A highly unpleasant human-monster nightmare-fly thing that can walk over walls and ceilings. It uses air-ducts to travel around quickly and eviscerates assailants with its really sharp claws. Can't kick a ball to save its life, though.
Movie monster we'd like to see it have a fight with...
Turkey-Head Mutant-Thing (Blood Freak, 1972)
Who would win? The Chimera would probably shade this one. In the film, a man eats a turkey laced with experimental drugs and becomes Turkey-Head Mutant Thing.
He then kills people in disappointingly un-turkeyish ways. Chimera would just yank out his guts, shove some Paxo up his arse and slam him into a big oven.