5. Kraven The Hunter
History: Kraven is a crazed big game hunter who wants to capture and kill our hero to prove he’s the best hunter in the world. Uses a serum similar to Spider-Man’s to give him super-strength and agility.
Why he’s a fit for Sam Raimi’s Spiderman: He’s already been updated in the Ultimate universe as the host of a reality show who hunts down dangerous animals and considers Spider-Man to be the ultimate trophy. That’s a pretty good starting point for Spider-Man 4.
Who should play him: Another X-Men alumni, Hugh Jackman. Like the modern Kraven, Jackman is Australian and has just the right mix of theatricality and menace to make him credible.